|Season 1||Season 2||Episode Guide|
Season 2 of Gabby Duran & The Unsittables was officially announced by Variety on October 7th, 2019 ahead of the series premiere.  Production began on January 28, 2020, but was halted due to COVID-19, later resumed on October 2, 2020, and wrapped on March 13, 2021. The 20 episode season premiered on June 4, 2021.
In season two, a resourceful and courageous Gabby faces even bigger challenges as she continues to protect her alien charges while also navigating the everyday emotional rollercoaster of middle school. The season picks up immediately after a cliffhanger with Gabby's mom, Dina, on the verge of learning Gabby's secret, which the intrepid teen will have to stop in order to avoid catastrophic outcomes. Other adventures this season will include a robot replica Gabby-bot running amok, an alien friend who turns into a "Predator" when she becomes emotional, and a quest to recover Principal Swift's home after it's shrunken down to the size of a dollhouse by an extraterrestrial prankster.
- Kylie Cantrall as Gabby Duran
- Coco Christo as Olivia Duran
- Maxwell Acee Donovan as Wesley
- Callan Farris as Jeremy
- Nathan Lovejoy as Principal Swift
- Valery Ortiz as Dina Duran
- Elle McKinnon as Sky
- Bracken Hanke as Susie Glover
- Mia Bella as Kali
- Jeremy Davis as Howard
- Kheon Clarke as Julius
- Brent Clark as Sky's Dad
- Laara Sadiq as Orb (voice)
- Sabrina Pitre as Fritz (voice)
- Ricardo Ortiz as Jace
These are episodes that have confirmed titles and dates.
- 06/04/21 - Mom Wipe (201)
- 06/11/21 - Gabby's Big Break (202)
- 06/18/21 - The Vibe (203)
- 06/25/21 - Ratita and the Ultras (204)
- 07/02/21 - Mimi from Miami (205)
- 07/09/21 - The Mile (207)
- 07/16/21 - Dude, Where's My House? (208)
- 07/30/21 - A Song of Gabby & Susie (209)
- 08/06/21 - The Bubble (210)
- 08/06/21 - GOAT of the Month (211)
These are episodes that have been confirmed but do not have dates.
- Beware the Fright Master! (206)
- Dinas and Dougs (212)
- Zeke to the Future (213)
- Adventures in Alien House-Sitting (214)
- Fountain of Ruth (215)
- Extreme Ruckus (216)
- Welcome to the Club (217)
- Shoe-Dun-It (218)
- Magic Hours (219)
- The Fault in Our Star Night (220-221)
- This season was officially announced before the series premiere making it the first Disney Channel live-action series to be renewed before it's season premieres in 2019 while the second was Sydney to the Max. However, the season did not premiere until over a year since the first season ended.
- Production began on January 28, 2020, but was halted, resuming on October 2, 2020, and wrapped on March 13, 2021.
- The season picked up right where "Enter the Dranis" left off.